The problem is actually in your low mids and sub 100Hz and it's throwing your perception in the upper regions. This is fatiguing. That said, there's a lot of harshness hiding in the stock materials from excessive processing. It's already been heavily manhandled (read "mixed") and it pays to take this into account whenever touching any parameter.....damage on top of damage stacks up. The trouble is, the brain gets used to it very quickly. Then chuck in the habituation effect and it's all out of control pretty quickly.
For me, the arrangement and production values require a critique. The bgtr is being mirrored by a lead, and on occasion there's a lead mirroring an acgtr. This offers nothing emotionally, and robs the sound stage of essential headroom and instead dumps relentless sonic clutter from not only the fundamentals, but all those harmonics!! And it's got you by the nuts.
I'd suggest reviewing your listening environment because these things should be jumping out at you for attention. Are you on headphones perhaps? There's some characteristics that lead me in this direction
If you listen to @mikej's clickbait, he has a very similar problem. Auditioned over decent equipment (Naim into Neutron III's and sub), it's a catastrophe. However, there's a significant amount of spectral skew in the stock. Cutting this out is challenging because of the fistfulls of added distortion that comes from large compensation measures. But when (and if) you do, your perspectives above 500Hz will be transformed. And then that's another problem. Distortion artifacts from excess saturation become increasingly exposed.....everything has been cooked to death. I wish we'd had the recordings rather than someone's mix to mix which can never end well.
All good fun, eh?
It needs an intro....something...anything!! Shame on you